Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 17/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603121 | 0.80 | OPRD1 (0.62) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL1603304 | 0.78 | OPRD1 (0.60) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL1603518 | 0.74 | OPRD1 (0.59) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL1603161 | 0.74 | OPRD1 (0.74) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL4932328 | 0.73 | OPRD1 (0.73) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL1603684 | 0.71 | OPRD1 (0.61) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL6610713 | 0.71 | OPRD1 (0.71) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL4923000 | 0.71 | OPRD1 (0.65) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL5727063 | 0.70 | OPRD1 (0.69) | OPRD1OPRM1KCNH2OPRK1 | |
| SCHEMBL5370140 | 0.70 | OPRD1 (0.69) | OPRD1OPRM1KCNH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641757-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF | AstraZeneca AB (SE) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004101522-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-11-25 | — | — | WO | disclosed |