SCHEMBL5824246 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	APP	P05067	1/20	0.37

▸	PTGS2	P35354	6/20	0.33

▸	RORC	P51449	1/20	0.33

▸	PTGS1	P23219	1/20	0.32

▸	SRC	P12931	2/20	0.32

▸	PRKACA	P17612	2/20	0.32

▸	PRKACG	P22612	2/20	0.32

▸	PRKACB	P22694	2/20	0.32

▸	AKR1C3	P42330	2/20	0.32

▸	AKR1C2	P52895	2/20	0.32

▸	ABCB1	P08183	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5797453	0.94	APP (0.37)	APPPTGS2PTGS1SRCPRKACA
SCHEMBL5798692	0.91	APP (0.37)	APPPTGS2SRCPRKACAPRKACG
SCHEMBL5809014	0.90	PTGS2 (0.42)	APPPTGS2PTGS1AKR1C3AKR1C2
SCHEMBL5809718	0.89	PTGS2 (0.36)	PTGS2RORCPTGS1AKR1C3AKR1C2
SCHEMBL5809713	0.89	PTGS2 (0.36)	PTGS2RORCPTGS1AKR1C3AKR1C2
SCHEMBL5822629	0.89	PTGS2 (0.42)	APPPTGS2RORCPTGS1AKR1C3
SCHEMBL5549724	0.88	PTGS2 (0.43)	APPPTGS2RORCPTGS1SRC
SCHEMBL5562383	0.88	PTGS2 (0.43)	APPPTGS2RORCPTGS1SRC
SCHEMBL5554383	0.88	PTGS2 (0.43)	APPPTGS2RORCPTGS1SRC
SCHEMBL5814225	0.88	APP (0.39)	APPPTGS2SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2006050120-A2	SYNTHESIS OF COX-2 AND FAAH INHIBITORS	MICROBIA, INC. (US)	2006-05-11	—	—	WO	disclosed