SCHEMBL58243

SCHEMBL58243

Clc1[c]cc(Cl)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1024917 0.75
SCHEMBL11530245 0.75
SCHEMBL8567751 0.73
SCHEMBL1392503 0.71
SCHEMBL3393602 0.71 KDM4E (0.32)
SCHEMBL15991986 0.71 HPGD (0.36) CYP3A4
SCHEMBL5917285 0.71 CYP3A4 (0.31) CYP3A4
SCHEMBL2238360 0.71 CYP3A4 (0.32) CYP3A4
SCHEMBL10566551 0.69
SCHEMBL1906356 0.68 AHR (0.48) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957632-B Glycolic acid modified unsaturated polymer and preparation method and application thereof 华润化学材料科技股份有限公司 2024-02-02 CN claimed
US-20230296983-A1 PHOTOSENSITIVE POLYMER, PHOTORESIST COMPOSITION INCLUDING THE SAME, AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-21 US claimed
CN-106232120-B Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones 爱尔皮奥治疗有限公司 2021-01-08 CN claimed
WO-2020079669-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2020-04-23 WO claimed
CN-109651331-A A kind of glaucocalyxin A derivative and its preparation method and application 中国人民解放军军事科学院军事医学研究院 2019-04-19 CN claimed
EP-3408345-A1 TRACER AND METHOD Johnson Matthey Public Limited Company (GB) 2018-12-05 EP claimed
WO-2017129944-A1 TRACER AND METHOD JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2017-08-03 WO claimed
US-20170079954-A1 PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS AXIKIN PHARMACEUTICALS, INC. 2017-03-23 US claimed
US-9540351-B2 Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors AXIKIN PHARMACEUTICALS, INC. (US) 2017-01-10 US claimed
EP-3107542-A1 PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES Aerpio Therapeutics, Inc. (US) 2016-12-28 EP claimed
US-4226761-A Polyphenylene ether resin compositions containing polysiloxane-modified alkenyl aromatic resins GENERAL ELECTRIC COMPANY (US) 1980-10-07 US claimed
US-4208342-A Polyethylene silicon compounds RHONE-POULENC INDUSTRIES (FR) 1980-06-17 US claimed
US-4145508-A Polysiloxane thermoplastic elastomers RHONE-POULENC INDUSTRIES (FR) 1979-03-20 US claimed
US-4138349-A FOR LUBRICATING SOFT METALS SUCH AS COPPER OR BRONZE GENERAL ELECTRIC COMPANY (US) 1979-02-06 US claimed
US-4102893-A Process for the manufacture of color formers of indoles and anhydrides of aromatic or heteroaromatic, vicinal dicarboxylic acids, new color formers of these classes of substance and their use CIBA-GEIGY AG (CH) 1978-07-25 US claimed
US-4071316-A Silicone composition for analyzing blood samples GENERAL ELECTRIC COMPANY (US) 1978-01-31 US claimed
US-4060623-A 1,2,4-Triazole antimycotic compositions and use thereof BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US claimed
US-4038404-A 1,2,4-TRIAZOLE ANTIMYCOTIC COMPOSITIONS AND USE THEREOF BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US claimed
US-4036966-A 1,2,4-Triazole antimycotic compositions and use thereof BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US claimed
US-4036967-A 1,2,4-Triazole antimycotic compositions and use thereof BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170079954-A1 PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS GRK3, DMPK, PRKAG3 CYP3A4 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.