SCHEMBL5824324

SCHEMBL5824324

C=CCOC(=O)/C=C(\C)CP(=O)(OCC=C)OCC=C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
TSHR P16473 1/20 0.33
CYP3A4 P08684 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
APP P05067 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2879352 0.77 TSHR (0.32) TSHR
SCHEMBL15482484 0.75 TSHR (0.42) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL711893 0.75 NPSR1 (0.44) MAPTTSHRPKM
SCHEMBL2079724 0.75 NPSR1 (0.44) MAPTTSHRPKM
SCHEMBL9491837 0.74 MAPT (0.41) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL9491841 0.74 MAPT (0.41) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL11873857 0.74 MAPT (0.41) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL6050174 0.73 MAPT (0.46) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL15482672 0.73 TSHR (0.47) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL15482576 0.71 TDP1 (0.42) MAPTCACNA1BAPBA1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984742-B2 Method for preparing polyprenyl compounds NIKKEN CHEMICALS CO., LTD. (JP) 2006-01-10 US disclosed
US-20040242690-A1 Method for preparing polyprenyl compounds NIKKEN CHEMICALS CO., LTD. (JP) 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242690-A1 Method for preparing polyprenyl compounds CYP11B2, CBR1, CUL2 MAPT 2566/4885CACNA1B 4189/4885APBA1 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.