SCHEMBL5825879

SCHEMBL5825879

O=C=Nc1ccsc1N=C=O

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.40
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11431753 0.76
SCHEMBL125480 0.76
SCHEMBL5781083 0.76
SCHEMBL4971535 0.76
SCHEMBL3044779 0.76
SCHEMBL10704182 0.72 MEN1 (0.35) ALDH1A1HPGD
SCHEMBL12006338 0.72 GABRA1 (0.47) CYP3A4TSHR
SCHEMBL6871094 0.71 CTNNB1 (0.32)
SCHEMBL8938713 0.71 CYP3A4 (0.35) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL16413176 0.71 PTPN2 (0.41) CYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108276543-A Glass lens polythiol compositions SKC株式会社 2018-07-13 CN disclosed
CN-104640900-A Preparation method of thiourethane optical material KOC SOLUTION CO LTD 2015-05-20 CN disclosed
JP-2006257004-A METHOD FOR PRODUCING HETEROCYCLIC DIISOCYANATE TOYO KASEI KOGYO CO LTD 2006-09-28 JP disclosed
JP-2005171055-A COMPOSITION FOR TRANSPARENT RESIN HAVING HIGH REFRACTIVE INDEX AND HIGH HEAT RESISTANCE MITSUI CHEMICALS INC 2005-06-30 JP disclosed
JP-2005154692-A COMPOSITION FOR TRANSPARENT RESIN HAVING HIGH REFRACTIVE INDEX MITSUI CHEMICALS INC 2005-06-16 JP disclosed