Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.61 |
| ▸ | MET | P08581 | 6/20 | 0.57 |
| ▸ | AXL | P30530 | 4/20 | 0.55 |
| ▸ | MERTK | Q12866 | 3/20 | 0.55 |
| ▸ | KIT | P10721 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | LYN | P07948 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HCK | P08631 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5825578 | 0.93 | PDGFRA (0.59) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5826191 | 0.91 | PDGFRA (0.57) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5825683 | 0.91 | KDR (0.61) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5825780 | 0.90 | PDGFRA (0.55) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5825830 | 0.90 | PDGFRA (0.57) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5825775 | 0.88 | PDGFRA (0.57) | KDRPDGFRAMETKITEGFR | |
| SCHEMBL5825647 | 0.87 | KDR (0.64) | KDRPDGFRAMETAXLMERTK | |
| SCHEMBL5826008 | 0.87 | PDGFRA (0.56) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5825601 | 0.86 | PDGFRA (0.55) | KDRPDGFRAMETAXLKIT | |
| SCHEMBL5825746 | 0.86 | PDGFRA (0.54) | KDRPDGFRAMETAXLKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | claimed |