Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 11/20 | 0.57 |
| ▸ | KDR | P35968 | 10/20 | 0.57 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5825938 | 0.96 | PDGFRA (0.58) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5825775 | 0.92 | PDGFRA (0.57) | PDGFRAKDRKITFGFR2MET | |
| SCHEMBL5825985 | 0.91 | KDR (0.61) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5825578 | 0.88 | PDGFRA (0.59) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5825780 | 0.87 | PDGFRA (0.55) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5825830 | 0.86 | PDGFRA (0.57) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5825683 | 0.85 | KDR (0.61) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5824865 | 0.85 | PDGFRA (0.61) | PDGFRAKDRAXLFGFR2 | |
| SCHEMBL5826049 | 0.85 | PDGFRA (0.48) | PDGFRAKDRKITAXLFGFR2 | |
| SCHEMBL5826187 | 0.85 | KDR (0.48) | PDGFRAKDRKITAXLFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | claimed |