SCHEMBL582774

SCHEMBL582774

O=C(O)CCOC(=O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.70
LMNA P02545 2/20 0.66
MAPK1 P28482 1/20 0.57
HIF1A Q16665 1/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.53
F2 P00734 1/20 0.52
NR4A2 P43354 1/20 0.52
TSHR P16473 2/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KDM4E B2RXH2 1/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28525418 0.98 TDP1 (0.68) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL28156890 0.91 TDP1 (0.57) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL25371286 0.89 TDP1 (0.61) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL4222754 0.88 TDP1 (0.78) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL137486 0.87 TDP1 (0.83) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL11264826 0.86 TDP1 (0.52) TDP1LMNAMAPK1SLC6A2ALDH1A1
SCHEMBL11876158 0.86 TDP1 (0.68) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL6935004 0.86 TDP1 (0.68) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL6327206 0.85 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL8013431 0.85 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978880-A Inorganic silicate anti-skinning agent and application thereof in anti-insolation anti-skinning inorganic silicate paint 立邦涂料(四川)有限公司 2025-05-13 CN claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
CN-119978880-A Inorganic silicate anti-skinning agent and application thereof in anti-insolation anti-skinning inorganic silicate paint 立邦涂料(四川)有限公司 2025-05-13 CN disclosed
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
CN-110998800-B Polishing liquid, polishing liquid set and polishing method 株式会社力森诺科 2023-09-22 CN disclosed
US-11649377-B2 Polishing liquid, polishing liquid set and polishing method RESONAC CORPORATION (JP) 2023-05-16 US disclosed
US-20200299544-A1 POLISHING LIQUID, POLISHING LIQUID SET AND POLISHING METHOD RESONAC CORPORATION (JP) 2020-09-24 US disclosed
CN-109970921-A A kind of high water reduction muting sensitive sense polycarboxylate water-reducer and preparation method thereof 科之杰新材料集团有限公司 2019-07-05 CN disclosed
US-20170133237-A1 POLISHING LIQUID AND METHOD FOR POLISHING SUBSTRATE USING THE POLISHING LIQUID HITACHI CHEMICAL CO LTD (JP) 2017-05-11 US disclosed
US-9564337-B2 Polishing liquid and method for polishing substrate using the polishing liquid HITACHI CHEMICAL CO., LTD. (JP) 2017-02-07 US disclosed
WO-2016115090-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR INCREASING CFTR ACTIVITY PROTEOSTASIS THERAPEUTICS, INC. (US) 2016-07-21 WO disclosed
EP-1369906-B1 POLISHING COMPOUND AND METHOD FOR POLISHING SUBSTRATE HITACHI CHEMICAL CO LTD (JP) 2012-06-27 EP disclosed
EP-2418258-A1 Polishing slurry and method of polishing substrate Hitachi Chemical Company, Ltd. (JP) 2012-02-15 EP disclosed
US-20080154049-A1 for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes. SHASUN PHARMA SOLUTIONS LIMITED (GB) 2008-06-26 US disclosed
US-6786945-B2 Polishing compound and method for polishing substrate HITACHI CHEMICAL CO., LTD. (JP) 2004-09-07 US disclosed
US-20040065022-A1 Polishing compound and method for polishing substrate HITACHI CHEMICAL CO., LTD. (JP) 2004-04-08 US disclosed
EP-1369906-A1 POLISHING COMPOUND AND METHOD FOR POLISHING SUBSTRATE HITACHI CHEMICAL COMPANY, LTD. (JP) 2003-12-10 EP disclosed
CN-1096292-C Method for preparing bimetallic ruthenium/tin catalyst PHODIA CHIMIE (FR) 2002-12-18 CN disclosed
US-6180830-B1 REDUCING COMPLEX OF RUTHENIUM HAVING ELECTROVALENCY OF-4 AND COORDINATION NUMBER OF 6, WHEREIN AT LEAST ONE LIGAND IS TIN HALIDE, OTHER LIGANDS OPTIONALLY BEING HALOGEN ATOMS RHODIA CHIMIE (FR) 2001-01-30 US disclosed
CN-1204271-A Method for preparing bimetallic ruthenium/tin catalyst PHODIA CHIMIE (FR) 1999-01-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154049-A1 for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes. AADAC, APEH, DDC TDP1 4532/4885LMNA 1577/4885MAPK1 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.