Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL5828566

C=CCCO.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LPAR3 Q9UBY5 2/20 0.45
LPAR2 Q9HBW0 1/20 0.45
BTN3A1 O00481 4/20 0.37
PPARD Q03181 1/20 0.32
FNTA P49354 4/20 0.32
FNTB P49356 4/20 0.32
PGGT1B P53609 3/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27346285 0.85 LPAR3 (0.41) LPAR3LPAR2BTN3A1TSHR
Pyrophosphoric Acid SCHEMBL8752399 0.79 FDPS (0.46) FDPSBLMTDP1LPAR3LPAR2
Pyrophosphoric Acid SCHEMBL31121685 0.79 BTN3A1 (0.39) LPAR3LPAR2BTN3A1
Pyrophosphoric Acid SCHEMBL7091560 0.78 FDPS (0.50) FDPSBLMTDP1LPAR3LPAR2
Pyrophosphoric Acid SCHEMBL8837385 0.76 FDPS (0.71) FDPSBLMTDP1BTN3A1PPARD
Pyrophosphoric Acid SCHEMBL2575783 0.76 FDPS (0.71) FDPSBLMTDP1BTN3A1PPARD
SCHEMBL11589496 0.76 TSHR (0.50) TSHR
SCHEMBL1836 0.76
Pyrophosphoric Acid SCHEMBL8676547 0.75 FDPS (0.53) FDPSBLMTDP1LPAR3LPAR2
Pyrophosphoric Acid SCHEMBL1443727 0.75 FDPS (0.53) FDPSBLMTDP1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998471-B2 Polynucleotides encoding an acetyl-CoA acetyltransferase from Hevea brasiliensis, related products, and methods E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-02-14 US disclosed
EP-1434784-A4 GENES INVOLVED IN THE BIOSYNTHESIS OF ISOPENTENYL DIPHOSPHATE IN HEVEA BRASILIENSIS LATEX DU PONT (US) 2005-06-29 EP disclosed
EP-1434784-A2 GENES INVOLVED IN THE BIOSYNTHESIS OF ISOPENTENYL DIPHOSPHATE IN HEVEA BRASILIENSIS LATEX E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-07-07 EP disclosed
US-20030119098-A1 Genes involved in the biosynthesis of isopentenyl diphosphate in Hevea brasiliensis latex HALLAHAN DAVID L (US) 2003-06-26 US disclosed
WO-2003010294-A2 GENES INVOLVED IN THE BIOSYNTHESIS OF ISOPENTENYL DIPHOSPHATE IN HEVEA BRASILIENSIS LATEX E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-06 WO disclosed