Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828903 | 1.00 | CYP19A1 (0.51) | CYP19A1NPBWR1MAPTNPSR1CYP1A2 | |
| SCHEMBL5829122 | 0.83 | CYP19A1 (0.47) | CYP19A1MAPTNPSR1CYP1A2CYP2D6 | |
| SCHEMBL5829127 | 0.83 | CYP19A1 (0.47) | CYP19A1MAPTNPSR1CYP1A2CYP2D6 | |
| SCHEMBL27848309 | 0.83 | CYP19A1 (0.58) | CYP19A1NPBWR1MAPTNPSR1CYP1A2 | |
| SCHEMBL28173938 | 0.83 | CYP19A1 (0.58) | CYP19A1NPBWR1MAPTNPSR1CYP1A2 | |
| SCHEMBL5828579 | 0.81 | CTSV (0.48) | NPBWR1MAPTNPSR1MAPK1MEN1 | |
| SCHEMBL5828582 | 0.81 | CTSV (0.48) | NPBWR1MAPTNPSR1MAPK1MEN1 | |
| SCHEMBL5829057 | 0.80 | CTSV (0.49) | NPBWR1MAPTNPSR1CYP1A2CYP2D6 | |
| SCHEMBL5829053 | 0.80 | CTSV (0.49) | NPBWR1MAPTNPSR1CYP1A2CYP2D6 | |
| SCHEMBL701421 | 0.79 | CYP2A6 (0.51) | MAPTNPSR1CYP1A2CYP2D6IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094798-B1 | Inhibitors of checkpoint kinases (Wee1 and Chk1) | PFIZER INC (US) | 2006-08-22 | — | — | US | disclosed |