Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004766 | 0.90 | NPC1 (0.52) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL5324109 | 0.84 | NPC1 (0.47) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL22662185 | 0.82 | NPC1 (0.46) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL9442082 | 0.82 | NPC1 (0.50) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL8125577 | 0.82 | NPC1 (0.46) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL1324 | 0.80 | NPC1 (0.62) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL10784714 | 0.79 | NPC1 (0.47) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL1491811 | 0.78 | — | — | |
| Bromide SCHEMBL7371333 | 0.78 | NPC1 (0.60) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL16266978 | 0.78 | NPC1 (0.60) | NPC1RAB9AKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39333-E1 | Process for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives | KANEKA CORPORATION (JP) | 2006-10-10 | — | — | US | disclosed |
| EP-1104750-B1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORP (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6340767-B1 | REACTION OF LITHIUM AMIDE WITH ACETIC ACID ESTER AND HYDROXY PROPIONIC ACID | KANEKA CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1104750-A1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-4514382-A | IMIDAZOLE DERIVATIVE | COLGATE-PALMOLIVE COMPANY (US) | 1985-04-30 | — | — | US | disclosed |