⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28012860 | 1.00 | — | — | |
| Formic Acid SCHEMBL2511100 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL1545886 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL83909 | 0.94 | — | — | |
| Formic Acid SCHEMBL1064783 | 0.94 | — | — | |
| Formic Acid SCHEMBL811681 | 0.94 | — | — | |
| Formic Acid SCHEMBL1545869 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL18112628 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL394887 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL582126 | 0.94 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985306-B | The fully synthetic preparation method of natural products flavone compound | 复旦大学 | 2018-10-26 | — | — | CN | claimed |
| CN-105985306-A | Total synthesis preparation method of natural product flavonoid compounds | 复旦大学 | 2016-10-05 | — | — | CN | claimed |
| WO-2024081372-A1 | PROCESSES FOR THE PREPARATION OF THE AGENT-LINKER CONJUGATE CL2A-SN-38 AND THE IMMUNOCONJUGATES SACITUZUMAB GOVITECAN AND LABETUZUMAB GOVETICAN | GILEAD SCIENCES, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-117616013-A | Hydrogenated quinoxalines | 大塚制药株式会社 | 2024-02-27 | — | — | CN | disclosed |
| WO-2022224035-A2 | ANTI-GM1 ANTIBODY BINDING COMPOUNDS | POLYNEURON PHARMACEUTICALS AG (CH) | 2022-10-27 | — | — | WO | disclosed |
| CN-110437144-B | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2021-03-26 | — | — | CN | disclosed |
| WO-2020212697-A1 | INHIBITOR COMPOUNDS | Azeria Therapeutics Limited (GB) | 2020-10-22 | — | — | WO | disclosed |
| CN-105985306-B | The fully synthetic preparation method of natural products flavone compound | 复旦大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-105985306-A | Total synthesis preparation method of natural product flavonoid compounds | 复旦大学 | 2016-10-05 | — | — | CN | disclosed |
| CN-103772379-B | A kind of preparation method of trospium chloride key intermediate | 寿光富康制药有限公司 | 2016-06-15 | — | — | CN | disclosed |
| WO-2014141118-A1 | IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-09-18 | — | — | WO | disclosed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4965270-A | Viricides | BEECHAM GROUP P.L.C. (GB) | 1990-10-23 | — | — | US | disclosed |
| US-4910307-A | Process for preparing purines | BEECHAM GROUP P.L.C. (GB) | 1990-03-20 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |
| EP-0319228-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-06-07 | — | — | EP | disclosed |
| EP-0313289-A2 | Process for the preparation of purine compounds and intermediates therefor | BEECHAM GROUP PLC (GB) | 1989-04-26 | — | — | EP | disclosed |
| EP-0242482-A2 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |