Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6391281 | 1.00 | MEN1 (0.39) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6394139 | 0.88 | MEN1 (0.37) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6390850 | 0.86 | MEN1 (0.39) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL4846865 | 0.85 | MEN1 (0.39) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7069371 | 0.85 | MEN1 (0.39) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6413955 | 0.85 | MEN1 (0.39) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6807107 | 0.84 | KDM4E (0.34) | ALDH1A1RECQL | |
| SCHEMBL1405996 | 0.76 | — | — | |
| SCHEMBL5664385 | 0.76 | — | — | |
| SCHEMBL1405743 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067290-B2 | Method for production of polyketides | KOSAN BIOSCIENCES INCORPORATED (US) | 2006-06-27 | — | — | US | disclosed |