Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413955 | 1.00 | MEN1 (0.39) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL7069371 | 1.00 | MEN1 (0.39) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL6394139 | 0.88 | MEN1 (0.37) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL5500614 | 0.86 | PAOX (0.35) | ALDH1A1HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL4817591 | 0.86 | PAOX (0.35) | ALDH1A1HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL6390850 | 0.86 | MEN1 (0.39) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL5829703 | 0.85 | MEN1 (0.39) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL6391281 | 0.85 | MEN1 (0.39) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL599199 | 0.78 | CHRM1 (0.50) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL13747951 | 0.78 | CHRM1 (0.50) | HDAC1HDAC2CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459294-B2 | Method of producing a compound by fermentation | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-12-02 | — | — | US | disclosed |
| US-20050130283-A1 | Method of producing a compound by fermentation | KOSAN BIOSCIENCES, INC. (US) | 2005-06-16 | — | — | US | disclosed |