Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 16/20 | 1.00 |
| ▸ | ICAM1 | P05362 | 16/20 | 1.00 |
| ▸ | ITGAL | P20701 | 16/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830529 | 0.94 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2ALMNA | |
| SCHEMBL5830259 | 0.90 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2ALMNA | |
| SCHEMBL5830335 | 0.88 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2ALMNA | |
| SCHEMBL6312299 | 0.83 | ITGB2 (0.82) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL5829930 | 0.81 | ITGB2 (0.70) | ITGB2ICAM1ITGALKMT2ALMNA | |
| SCHEMBL5829927 | 0.81 | ITGB2 (0.68) | ITGB2ICAM1ITGALKMT2ALMNA | |
| SCHEMBL5830524 | 0.79 | ITGB2 (0.72) | ITGB2ICAM1ITGALKMT2ALMNA | |
| SCHEMBL6310646 | 0.79 | ITGAL (0.72) | ITGB2ICAM1ITGALLMNA | |
| SCHEMBL7662351 | 0.79 | ITGB2 (0.86) | ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL6317251 | 0.79 | ITGB2 (0.71) | ITGB2ICAM1ITGALKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39197-E1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2006-07-18 | — | — | US | disclosed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |