Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 17/20 | 0.72 |
| ▸ | ITGB2 | P05107 | 15/20 | 0.72 |
| ▸ | ICAM1 | P05362 | 15/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311339 | 0.89 | ITGAL (0.69) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6310393 | 0.89 | ITGAL (0.58) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6309487 | 0.88 | ITGB2 (0.58) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL5830529 | 0.84 | ITGB2 (1.00) | ITGALITGB2ICAM1LMNA | |
| SCHEMBL6317251 | 0.84 | ITGB2 (0.71) | ITGALITGB2ICAM1PYGL | |
| SCHEMBL6312299 | 0.81 | ITGB2 (0.82) | ITGALITGB2ICAM1PYGL | |
| SCHEMBL5830259 | 0.79 | ITGB2 (1.00) | ITGALITGB2ICAM1LMNA | |
| SCHEMBL5829935 | 0.79 | ITGB2 (1.00) | ITGALITGB2ICAM1LMNA | |
| SCHEMBL5830335 | 0.77 | ITGB2 (1.00) | ITGALITGB2ICAM1LMNA | |
| SCHEMBL7662351 | 0.75 | ITGB2 (0.86) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | claimed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |