Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8225761 | 0.90 | MEN1 (0.46) | TLR8KCNH2MAPTPARP1LIPG | |
| SCHEMBL18076729 | 0.90 | TLR8 (0.47) | TLR8KCNH2MAPTPARP1LIPG | |
| SCHEMBL3747524 | 0.89 | MEN1 (0.45) | TLR8KCNH2MAPTLIPGALOX5 | |
| Pyrene SCHEMBL4416467 | 0.89 | MEN1 (0.45) | TLR8KCNH2MAPTLIPGALOX5 | |
| SCHEMBL2177707 | 0.85 | MEN1 (0.47) | TLR8ERBB2CYP1A2FYNMAOA | |
| SCHEMBL5749026 | 0.84 | TLR8 (0.45) | TLR8KCNH2MAPTPARP1ERBB2 | |
| SCHEMBL5748158 | 0.84 | TLR8 (0.45) | TLR8KCNH2MAPTPARP1ERBB2 | |
| SCHEMBL5747752 | 0.84 | TLR8 (0.45) | TLR8KCNH2MAPTPARP1ERBB2 | |
| SCHEMBL5748485 | 0.81 | TLR8 (0.45) | TLR8KCNH2MAPTPARP1ERBB2 | |
| SCHEMBL5749563 | 0.81 | TLR8 (0.45) | TLR8KCNH2MAPTPARP1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135243-B2 | Organic electroluminescent devices | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-11-14 | — | — | US | disclosed |
| US-20050212409-A1 | Organic luminescent materials | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY, THE | 2005-09-29 | — | — | US | disclosed |
| US-20050214566-A1 | Organic electroluminescent devices | UNITED STATES GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050212409-A1 | Organic luminescent materials | CBR3, GALR3, REL | TLR8 2111/4885KCNH2 23/4885MAPT 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.