Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320415 | 0.84 | RET (0.41) | IDO1CYP19A1RETKDRCYP3A4 | |
| SCHEMBL17237773 | 0.77 | RAD52 (0.42) | CYP19A1RETKDRCYP3A4ALOX15 | |
| SCHEMBL3289417 | 0.77 | CYP3A4 (0.42) | CYP19A1RETKDRCYP3A4ALOX15 | |
| SCHEMBL2118993 | 0.73 | GNG2 (0.37) | RETKDRCYP3A4ALOX15ALDH1A1 | |
| SCHEMBL3197529 | 0.72 | CYP19A1 (0.46) | CYP19A1CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL28140395 | 0.72 | CYP3A4 (0.47) | IDO1CYP19A1RETKDRCYP3A4 | |
| SCHEMBL7762100 | 0.71 | IDO1 (0.38) | IDO1CYP19A1CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL30022103 | 0.71 | IDO1 (0.38) | IDO1CYP19A1CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL6017369 | 0.70 | IDO1 (0.41) | IDO1CYP19A1CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL28459231 | 0.69 | SMN1; SMN2 (0.46) | CYP3A4ALOX15ALDH1A1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293493-A | With the inhibition active novel benzhydryl class compound of mycobacterium tuberculosis | 清华大学 | 2019-02-01 | — | — | CN | disclosed |
| US-20160143878-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-1732913-A1 | CHROMONE COMPLEXES | MERCK PATENT GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097772-A1 | CHROMONE COMPLEXES | MERCK PATENT GMBH (DE) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | MRPL21, Q6ZSR9, NQO2 | IDO1 2825/4885CYP19A1 1340/4885RET 3654/4885 |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | Q6ZSR9, MRPL21, NQO2 | IDO1 2786/4885CYP19A1 1498/4885RET 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.