Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 10/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849244 | 0.90 | ITGAL (0.50) | ITGALALDH1A1ITGB2ICAM1HPGD | |
| SCHEMBL6198447 | 0.86 | ITGAL (0.48) | ITGALALDH1A1MAPTITGB2ICAM1 | |
| SCHEMBL5830859 | 0.85 | ITGAL (0.57) | ITGALALDH1A1MAPTITGB2ICAM1 | |
| SCHEMBL6199249 | 0.83 | ITGAL (0.64) | ITGALMAPTITGB2ICAM1MEN1 | |
| SCHEMBL5830431 | 0.83 | ALDH1A1 (0.57) | ITGALALDH1A1MAPTITGB2ICAM1 | |
| SCHEMBL6199275 | 0.83 | ITGAL (0.64) | ITGALITGB2ICAM1 | |
| SCHEMBL6201358 | 0.83 | ITGAL (0.64) | ITGALALDH1A1ITGB2ICAM1HPGD | |
| SCHEMBL6196481 | 0.83 | ITGAL (0.64) | ITGALITGB2ICAM1 | |
| SCHEMBL6194517 | 0.82 | ITGAL (0.47) | ITGALALDH1A1ITGB2ICAM1HPGD | |
| SCHEMBL6194840 | 0.81 | ITGAL (0.45) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39197-E1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2006-07-18 | — | — | US | disclosed |