Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718882 | 0.87 | HSD17B10 (0.46) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL7928275 | 0.87 | KDM4E (0.49) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL20534991 | 0.85 | KDM4E (0.48) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL30608685 | 0.85 | KDM4E (0.48) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL25330745 | 0.85 | KDM4E (0.48) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL25330748 | 0.85 | KDM4E (0.48) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL29986418 | 0.85 | KDM4E (0.48) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL20535111 | 0.84 | MAOB (0.50) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL20897162 | 0.84 | KDM4E (0.45) | HSD17B10MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL20535109 | 0.84 | MAOB (0.50) | HSD17B10MAOBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094725-B2 | Biphenyldiphosphine compounds | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2006-08-22 | — | — | US | disclosed |
| US-20050014633-A1 | Biphenyldiphosphine compounds | HONG KONG POLYTECHNIC UNIVERSITY, THE (HK) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014633-A1 | Biphenyldiphosphine compounds | INPP5B, PCBP1, ITPA | HSD17B10 3405/4885MAOB 1539/4885KDM4E 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.