SCHEMBL5830852

SCHEMBL5830852

C=CCc1cccc2c(O)ccc(O)c12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.52
HPGD P15428 2/20 0.52
CASP1 P29466 2/20 0.52
HSD17B10 Q99714 2/20 0.52
APP P05067 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
SNCA P37840 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GABRA1 P14867 4/20 0.52
GABRB2 P47870 4/20 0.52
AKR1B1 P15121 2/20 0.47
POLB P06746 2/20 0.41
XDH P47989 1/20 0.40
KMT2A Q03164 6/20 0.40
GAA P10253 5/20 0.40
LMNA P02545 2/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409555 0.81 GABRA1 (0.55) MAPTHPGDCASP1HSD17B10APP
SCHEMBL7702615 0.81 GABRA1 (0.51) MAPTCASP1HSD17B10GABRA1GABRB2
SCHEMBL5843777 0.77 IDO1 (0.52) MAPTHPGDGABRA1GABRB2AKR1B1
SCHEMBL5831594 0.75 GABRA1 (0.56) MAPTCASP1HSD17B10GABRA1GABRB2
SCHEMBL31619949 0.75 GABRA1 (0.56) MAPTCASP1HSD17B10GABRA1GABRB2
SCHEMBL11331692 0.74 MAPT (0.52) MAPTHPGDCASP1HSD17B10APP
SCHEMBL168974 0.73 GABRA1 (0.79) MAPTHPGDCASP1HSD17B10ALOX15
SCHEMBL11223755 0.73 GABRA1 (0.55) MAPTCASP1HSD17B10GABRA1GABRB2
SCHEMBL29988109 0.73 GABRA1 (0.55) MAPTCASP1HSD17B10GABRA1GABRB2
SCHEMBL30443762 0.72 GABRA1 (0.59) MAPTHPGDCASP1HSD17B10GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed