⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butanol SCHEMBL14576807 | 0.86 | — | — | |
| Tert-Butanol SCHEMBL7683936 | 0.82 | FFAR3 (0.47) | — | |
| Tert-Butanol SCHEMBL2085430 | 0.82 | ALDH1A1 (0.33) | — | |
| Tert-Butanol SCHEMBL3628777 | 0.78 | — | — | |
| Tert-Butanol SCHEMBL788666 | 0.78 | ALDH1A1 (0.46) | — | |
| Tert-Butanol SCHEMBL282 | 0.78 | — | — | |
| Tert-Butanol SCHEMBL20503401 | 0.78 | ALDH1A1 (0.46) | — | |
| Chloroform SCHEMBL3164509 | 0.78 | — | — | |
| SCHEMBL48368 | 0.76 | — | — | |
| SCHEMBL204256 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106496158-B | Preparation method of 1,2, 4-benzothiadiazine series compounds | 江西师范大学 | 2019-07-16 | — | — | CN | claimed |
| CN-106496158-A | Preparation method of 1-aryl (alkyl) benzo [ e ] [1,2,4] thiadiazole-1-oxy series compounds | 江西师范大学 | 2017-03-15 | — | — | CN | claimed |
| US-20060188629-A1 | Method for the purification of sucralose | RICHMOND CHEMICAL CORPORATION | 2006-08-24 | — | — | US | claimed |
| WO-2024011218-A1 | POLYMERIC NANOPARTICLES FOR LONG ACTING DELIVERY OF A PEPTIDE AND METHODS OF MAKING AND USING THEREOF | BROWN UNIVERSITY (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023163140-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 | 2023-08-31 | — | — | WO | disclosed |
| CN-113057942-A | Nano-particles containing hydrophobic drug, composition and application thereof | 正大天晴药业集团股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| EP-2288340-B1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE LLC (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-2416650-B1 | NANOPARTICLE FORMULATIONS AND USES THEROF | ABRAXIS BIOSCIENCE LLC (US) | 2020-02-26 | — | — | EP | disclosed |
| CN-106496158-B | Preparation method of 1,2, 4-benzothiadiazine series compounds | 江西师范大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-105727303-B | A kind of high albumin composition for carrying Cabazitaxel drug and its preparation and preparation method | 四川科伦药物研究院有限公司 | 2019-06-28 | — | — | CN | disclosed |
| US-20180289620-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2018-10-11 | — | — | US | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |
| WO-2006057845-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5086045-A | Antitumor antibiotic | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5028536-A | Biosynthesis | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| US-5007714-A | Optical device | CANON KABUSHIKI KAISHA (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0387860-A2 | Antitumor antibiotic BMY-41339 | Bristol-Myers Squibb Company (US) | 1990-09-19 | — | — | EP | disclosed |
| US-4423038-A | Phosphoryl compounds, pharmaceutical preparations containing such compounds, and their use | CIBA-GEIGY CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |