Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833049 | 1.00 | HSD17B10 (0.51) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL2679928 | 0.82 | KDM4E (0.66) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL4140820 | 0.82 | KDM4E (0.66) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL1984486 | 0.80 | SLC7A5 (0.53) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL29475704 | 0.80 | SLC7A5 (0.53) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL1984487 | 0.80 | SLC7A5 (0.53) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL26664897 | 0.79 | USP2 (0.50) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL569807 | 0.79 | SLC7A5 (0.58) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL722789 | 0.78 | KDM4E (0.56) | HSD17B10KDM4EALOX15LMNAALDH1A1 | |
| SCHEMBL31189933 | 0.78 | KDM4E (0.56) | HSD17B10KDM4EALOX15LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050267035-A1 | Peptide and polypeptide inhibitors of complement C1s | ZYMOGENETICS, INC. | 2005-12-01 | — | — | US | claimed |
| EP-1349874-A2 | PEPTIDE AND POLYPEPTIDE INHIBITORS OF COMPLEMENT C1S | ZymoGenetics, Inc. (US) | 2003-10-08 | — | — | EP | claimed |
| US-20020102256-A1 | Peptide and polypeptide inhibitors of complement C1s | ZYMOGENETICS, INC. | 2002-08-01 | — | — | US | claimed |
| WO-2001098365-A2 | PEPTIDE AND POLYPEPTIDE INHIBITORS OF COMPLEMENT C1S | ZYMOGENETICS, INC. (US) | 2001-12-27 | — | — | WO | claimed |
| US-5858244-A | COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES | NALCO CHEMICAL COMPANY (US) | 1999-01-12 | — | — | US | claimed |
| US-5776875-A | Use of biodegradable polymers in preventing scale build-up | NALCO CHEMICAL COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| EP-0819653-A2 | Use of biodegradable polymers in preventing scale build-up | NALCO CHEMICAL COMPANY (US) | 1998-01-21 | — | — | EP | claimed |
| EP-2584037-B1 | METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME | RIKEN (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-9340790-B2 | Method for constructing recombinant bacterium for producing non-native protein, and utilization of same | RIKEN (JP) | 2016-05-17 | — | — | US | disclosed |
| EP-2584037-A1 | METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME | Riken (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-20130095524-A1 | METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME | RIKEN (JP) | 2013-04-18 | — | — | US | disclosed |
| US-7071299-B2 | Peptide and polypeptide inhibitors of complement C1s | ZYMOGENETICS, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050267035-A1 | Peptide and polypeptide inhibitors of complement C1s | ZYMOGENETICS, INC. | 2005-12-01 | — | — | US | disclosed |
| EP-1349874-A2 | PEPTIDE AND POLYPEPTIDE INHIBITORS OF COMPLEMENT C1S | ZymoGenetics, Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20020102256-A1 | Peptide and polypeptide inhibitors of complement C1s | ZYMOGENETICS, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2001098365-A2 | PEPTIDE AND POLYPEPTIDE INHIBITORS OF COMPLEMENT C1S | ZYMOGENETICS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| US-5858244-A | COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES | NALCO CHEMICAL COMPANY (US) | 1999-01-12 | — | — | US | disclosed |
| US-5776875-A | Use of biodegradable polymers in preventing scale build-up | NALCO CHEMICAL COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0819653-A2 | Use of biodegradable polymers in preventing scale build-up | NALCO CHEMICAL COMPANY (US) | 1998-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267035-A1 | Peptide and polypeptide inhibitors of complement C1s | C1S, C1QBP, C1R | HSD17B10 4791/4885KDM4E 4579/4885ALOX15 3472/4885 |
| US-20020102256-A1 | Peptide and polypeptide inhibitors of complement C1s | C1S, C1QBP, C1R | HSD17B10 4791/4885KDM4E 4579/4885ALOX15 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.