⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211415 | 0.87 | LMNA (0.41) | — | |
| SCHEMBL2760916 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL28987927 | 0.77 | — | — | |
| SCHEMBL9230931 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL18271797 | 0.77 | — | — | |
| SCHEMBL2101489 | 0.77 | — | — | |
| SCHEMBL3024 | 0.75 | — | — | |
| SCHEMBL6204482 | 0.75 | — | — | |
| SCHEMBL452616 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL4227023 | 0.73 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981939-B2 | Process for the preparation of 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl) oxy] benzonitrile (Crisaborole) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2021-04-20 | — | — | US | claimed |
| US-20200062785-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-[(1-HYDROXY-1,3-DIHYDRO-2,1-BENZOXABOROL-5-YL) OXY] BENZONITRILE (CRISABOROLE) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD., (IN) | 2020-02-27 | — | — | US | claimed |
| WO-2018207216-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-[(1-HYDROXY-1,3-DIHYDRO-2,1-BENZOXABOROL-5-YL) OXY] BENZONITRILE (CRISABOROLE) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2018-11-15 | — | — | WO | claimed |
| EP-0581980-B1 | 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid | NESTLE SA (CH) | 1999-03-03 | — | — | EP | claimed |
| EP-0581979-B1 | Quinic acid derivatives and process to prepare quinic acid derivatives | NESTLE SA (CH) | 1999-03-03 | — | — | EP | claimed |
| US-5446134-A | Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1995-08-29 | — | — | US | claimed |
| US-5401858-A | Preparation of quinic acid derivatives | NESTEC S.A. (CH) | 1995-03-28 | — | — | US | claimed |
| US-5395950-A | Production of quinic acid derivatives | NESTEC S.A. (CH) | 1995-03-07 | — | — | US | claimed |
| EP-0581980-A1 | 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1994-02-09 | — | — | EP | claimed |
| EP-0581979-A1 | Quinic acid derivatives and process to prepare quinic acid derivatives | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1994-02-09 | — | — | EP | claimed |
| US-20260034234-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | AGENSYS, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| US-20260021057-A1 | TRANSDERMAL DEVICE COMPRISING PRODRUG MOLECULES AND METHODS OF USING THE SAME | Remedy Diagnostics LLC (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4615439-A2 | SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS AND THEIR APPLICATIONS | Humanwell Pharmaceutical US, Inc. (US) | 2025-09-17 | — | — | EP | disclosed |
| EP-2970112-B1 | PHENYL CARBAMATE COMPOUND AND A COMPOSITION FOR PREVENTING OR TREATING A MEMORY LOSS-RELATED DISEASE COMPRISING THE SAME | BIO PHARM SOLUTIONS CO LTD (KR) | 2025-03-12 | — | — | EP | disclosed |
| EP-4423103-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | Maianti, Juan Pablo (US) | 2024-09-04 | — | — | EP | disclosed |
| US-4260605-A | ANTIINFLAMMATORY AGENTS, SULFONATION AND SUBSEQUENT ACYLATION OF SUBSTITUTED PREGNANE | AKZO N.V. (NL) | 1981-04-07 | — | — | US | disclosed |
| EP-0014005-A1 | Novel alkylated pregnanes, processes for their preparation and pharmaceutical compositions containing same | AKZO N.V. (NL) | 1980-08-06 | — | — | EP | disclosed |
| US-4203996-A | Synthetic cephalotaxine esters having antileukemic P388 activity | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1980-05-20 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4152333-A | ALKALOIDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1979-05-01 | — | — | US | disclosed |