Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.80 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091064 | 0.89 | SLC6A4 (1.00) | SLC6A4PDE7ASLC6A2SLC6A3 | |
| SCHEMBL5832916 | 0.76 | SLC6A4 (0.76) | SLC6A4PDE7ASLC6A2ALDH1A1MAPT | |
| SCHEMBL1645812 | 0.76 | SLC6A4 (0.77) | SLC6A4SLC6A2ALDH1A1SLC6A3 | |
| SCHEMBL5833050 | 0.75 | SLC6A4 (0.76) | SLC6A4PDE7ASLC6A2SLC6A3 | |
| SCHEMBL5833091 | 0.72 | SLC6A4 (0.58) | SLC6A4PDE7ASLC6A2ALDH1A1MAPT | |
| SCHEMBL7262800 | 0.72 | ALDH1A1 (0.60) | TAAR1ALDH1A1 | |
| SCHEMBL1644221 | 0.71 | SLC6A4 (0.69) | SLC6A4PDE7ASLC6A2SLC6A3 | |
| SCHEMBL1110747 | 0.70 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1644247 | 0.69 | PDE7A (0.56) | SLC6A4PDE7ASLC6A2ALDH1A1MAPT | |
| SCHEMBL1645804 | 0.67 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041851-B2 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-05-09 | — | — | US | disclosed |
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | SLC6A4, SLCO4C1, SLC6A2 | SLC6A4 1/4885PDE7A 1594/4885TAAR1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.