Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25085889 | 0.85 | CFTR (0.65) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL5833870 | 0.82 | CFTR (0.61) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL5841660 | 0.82 | CFTR (0.61) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL27454008 | 0.80 | CFTR (0.58) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL5833791 | 0.79 | CFTR (0.61) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL22263091 | 0.78 | CFTR (0.73) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL7575375 | 0.78 | NR4A2 (0.46) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL7574505 | 0.78 | RAB9A (0.46) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL5843160 | 0.78 | CFTR (0.63) | CFTRMRGPRX4KDM4ECES2ALDH1A1 | |
| SCHEMBL167426 | 0.77 | CFTR (0.71) | CFTRMRGPRX4KDM4ECES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153813-B2 | Substituted aryl ketones | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| CN-1646488-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | CN | disclosed |
| US-20050119129-A1 | For use as herbicides | BAYER CROPSCIENCE LP (DE) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119129-A1 | For use as herbicides | DDT, CBR1, CBR3 | CFTR 2138/4885MRGPRX4 2300/4885KDM4E 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.