Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194664 | 0.91 | — | — | |
| Sulfuric Acid SCHEMBL8360806 | 0.82 | TRPA1 (0.42) | TRPA1SLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL14651687 | 0.67 | TRPA1 (0.67) | TRPA1SLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL15867614 | 0.67 | TRPA1 (0.50) | TRPA1SLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL31074125 | 0.67 | — | — | |
| SCHEMBL11607846 | 0.67 | TRPA1 (0.50) | TRPA1SLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL1709048 | 0.67 | — | — | |
| SCHEMBL9715494 | 0.65 | — | — | |
| SCHEMBL29031602 | 0.65 | — | — | |
| SCHEMBL5838938 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101692-B2 | Identification of sortase gene | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-09-05 | — | — | US | disclosed |
| US-20060073530-A1 | Methods and compositions involving sortase B | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-06 | — | — | US | disclosed |
| US-6773706-B2 | Identification of sortase gene | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-08-10 | — | — | US | disclosed |
| US-20030022178-A1 | Identification of sortase gene | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-30 | — | — | US | disclosed |