SCHEMBL5834019

SCHEMBL5834019

CC(C)(C)OC(=O)N(I)CC1COCCN1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CTSS P25774 1/20 0.33
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26926319 0.85 CTSD (0.36) CTSDCTSLCTSBCTSSGAA
SCHEMBL16627450 0.83 CTSD (0.32) CTSDCTSLCTSBCTSS
SCHEMBL31048215 0.77 CTSD (0.34) CTSDCTSLCTSBCTSS
SCHEMBL18988730 0.76 GAA (0.33) GAA
SCHEMBL2334851 0.73 GAA (0.32) GAA
SCHEMBL6175782 0.72 GAA (0.40) GAA
SCHEMBL8570463 0.72 GAA (0.40) GAA
SCHEMBL6175779 0.72 GAA (0.40) GAA
SCHEMBL5098785 0.72 GRM2 (0.35)
SCHEMBL16059363 0.71 CTSD (0.35) CTSDCTSLCTSBCTSSGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7094780-B1 3-aminoquinazolin-2,4-dione antibacterial agents WARNER LAMBERT COMPANY LLC (US) 2006-08-22 US disclosed