Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.55 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.55 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258093 | 1.00 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9258412 | 0.98 | MEN1 (0.53) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10806879 | 0.95 | MEN1 (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8076076 | 0.95 | MEN1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8076106 | 0.95 | MEN1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8072876 | 0.95 | MEN1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8076372 | 0.95 | MEN1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8072244 | 0.95 | MEN1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8070971 | 0.95 | MEN1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8078024 | 0.93 | LMNA (0.58) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112701-B2 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-09-26 | — | — | US | claimed |
| EP-1483226-B1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-07 | — | — | EP | claimed |
| US-20050113608-A1 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-05-26 | — | — | US | claimed |
| US-6835857-B2 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-28 | — | — | US | claimed |
| US-20030171620-A1 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-09-11 | — | — | US | claimed |
| CN-119241363-A | Treprostinil derivative, and preparation method and application thereof | 长风药业(香港)有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-7112701-B2 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-09-26 | — | — | US | disclosed |
| US-7112701-B2 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-09-26 | — | — | US | disclosed |
| US-7112701-B2 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-09-26 | — | — | US | disclosed |
| EP-1483226-B1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-07 | — | — | EP | disclosed |
| EP-1483226-B1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-20050113608-A1 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-05-26 | — | — | US | disclosed |
| EP-1483226-A1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1483226-A1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074458-A1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003074458-A1 | IMPROVED METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE | BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) | 2003-09-12 | — | — | WO | disclosed |
| US-20030171620-A1 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-09-11 | — | — | US | disclosed |
| US-20030171620-A1 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-09-11 | — | — | US | disclosed |
| US-20030171620-A1 | Process for the manufacture of 4-(6-bromohexyloxy)-butylbenzene | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-09-11 | — | — | US | disclosed |
| WO-1995019336-A1 | PHENYL ETHANOL AMINE ETHERS AND USES THEREOF AS β-ADRENO-RECEPTOR AGONISTS | IOVIS BIOMEDICAL AND PHARMACEUTICAL CONSULTANTS (NL) | 1995-07-20 | — | — | WO | disclosed |