⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15836129 | 0.74 | — | — | |
| SCHEMBL21291556 | 0.70 | — | — | |
| SCHEMBL5077215 | 0.67 | — | — | |
| SCHEMBL1733584 | 0.65 | — | — | |
| SCHEMBL9687359 | 0.65 | — | — | |
| SCHEMBL16504060 | 0.62 | MAPT (0.34) | — | |
| SCHEMBL16592678 | 0.62 | — | — | |
| SCHEMBL1819677 | 0.55 | — | — | |
| SCHEMBL3117258 | 0.55 | — | — | |
| SCHEMBL5899081 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321408-B1 | 2-THIO-5-DIFLUOROMETHYLTHIO-1,3,4-THIADIAZOLES, AND NEMATOCIDAL AGENTS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1992-09-23 | — | — | EP | claimed |
| US-4910210-A | A 2-thio-5-difluoromethylthio-1,3,4-thiadiazole | CIBA-GEIGY CORP. (US) | 1990-03-20 | — | — | US | claimed |
| WO-2021155106-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION (US) | 2021-08-05 | — | — | WO | disclosed |
| CN-109563050-A | Amide salt compound, for the catalyst of polyurethane production and the production method of polyurethane resin | 广荣化学工业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| US-20150231114-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | PFIZER (US) | 2015-08-20 | — | — | US | disclosed |
| US-20150231114-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | PFIZER (US) | 2015-08-20 | — | — | US | disclosed |
| US-9096608-B2 | Pharmaceutically active pyrazolo-triazine derivatives | LEAD DISCOVERY CENTER GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-20150111873-A1 | PHARMACEUTICALLY ACTIVE PYRAZOLO-TRIAZINE DERIVATIVES | LEAD DISCOVERY CENTER GMBH (DE) | 2015-04-23 | — | — | US | disclosed |
| US-20130287700-A1 | COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM | KLINIKUM DARMSTADT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20120277231-A1 | QUINOLINYLOXYPHENYLSULFONAMIDES | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-11-01 | — | — | US | disclosed |
| US-7122711-B2 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20030158419-A1 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-21 | — | — | US | disclosed |
| EP-1312605-A1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-4910210-A | A 2-thio-5-difluoromethylthio-1,3,4-thiadiazole | CIBA-GEIGY CORP. (US) | 1990-03-20 | — | — | US | disclosed |