⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592678 | 0.61 | — | — | |
| SCHEMBL5077215 | 0.60 | — | — | |
| SCHEMBL11374672 | 0.55 | — | — | |
| SCHEMBL10433017 | 0.55 | — | — | |
| SCHEMBL23198641 | 0.54 | — | — | |
| SCHEMBL15836129 | 0.52 | — | — | |
| SCHEMBL3117258 | 0.50 | — | — | |
| SCHEMBL4645948 | 0.47 | — | — | |
| Methylene Chloride SCHEMBL18604011 | 0.43 | — | — | |
| Methylene Chloride SCHEMBL7983107 | 0.43 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110062761-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and their use as GLUN2B receptor modulators | 詹森药业有限公司 | 2019-07-26 | — | — | CN | disclosed |
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0337151-A2 | N-substituted phenyl-heterocyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |
| US-4307101-A | ANTIHISTAMINES AND ANTISECRETORY AGENTS OF THE THIOUREA OR UREA DERIVATIVES 5,6,7,8-TETRAHYDROIMIDAZO(1,5A)PYRIDINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-22 | — | — | US | disclosed |
| US-4293697-A | ANTIHISTAMINES | SMITH, KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4230865-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-28 | — | — | US | disclosed |
| US-4226874-A | ANTIHISTAMINES, ANTISECRETORY AGENTS, GASTRIC JUICE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-07 | — | — | US | disclosed |
| US-4151288-A | ANTHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |
| US-4137234-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |