Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777739 | 0.85 | TBXA2R (0.62) | TBXA2RPDE2APTGDR | |
| SCHEMBL5835835 | 0.79 | TBXA2R (0.60) | TBXA2RPDE2APTGDR | |
| SCHEMBL5836698 | 0.76 | TBXA2R (0.57) | TBXA2RPDE2APTGDR | |
| SCHEMBL5834967 | 0.74 | TBXA2R (0.38) | TBXA2R | |
| SCHEMBL5834981 | 0.67 | TBXA2R (0.56) | TBXA2RPTGDR | |
| SCHEMBL5835634 | 0.67 | TBXA2R (0.56) | TBXA2RPTGDR | |
| SCHEMBL5835468 | 0.64 | TBXA2R (0.35) | TBXA2R | |
| SCHEMBL5473758 | 0.63 | PTGDR2 (0.66) | PTGDR | |
| SCHEMBL718296 | 0.62 | PPARA (0.67) | LMNAALDH1A1HPGDPPARA | |
| SCHEMBL5778603 | 0.61 | TBXA2R (0.51) | TBXA2RPDE2APTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |