Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 18/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837002 | 0.89 | TBXA2R (0.71) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5834981 | 0.89 | TBXA2R (0.56) | TBXA2RPTGDRPTGDR2PTGER1PTGER3 | |
| SCHEMBL5777618 | 0.83 | TBXA2R (0.79) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5835835 | 0.81 | TBXA2R (0.60) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5836996 | 0.79 | TBXA2R (0.58) | TBXA2RPTGDR | |
| SCHEMBL5835524 | 0.79 | TBXA2R (0.57) | TBXA2RPTGDR | |
| SCHEMBL5836698 | 0.78 | TBXA2R (0.57) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5776305 | 0.78 | TBXA2R (0.57) | TBXA2RPTGDRPTGDR2PTGER1PTGER3 | |
| SCHEMBL5835854 | 0.77 | TBXA2R (0.56) | TBXA2RPTGDR | |
| SCHEMBL5835832 | 0.75 | TBXA2R (0.56) | TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |