Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584550 | 0.94 | EPHX1 (0.73) | EPHX1POLBRAB9ANPC1HPGD | |
| SCHEMBL12196182 | 0.80 | EPHX1 (1.00) | EPHX1POLBRAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL4862364 | 0.78 | PTPN1 (0.60) | RAB9ANPC1PTPN1ALDH1A1MEN1 | |
| SCHEMBL584201 | 0.78 | EPHX1 (0.71) | EPHX1POLBRAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL4856338 | 0.76 | MEN1 (0.60) | POLBRAB9ANPC1PTPN1ALDH1A1 | |
| SCHEMBL6436349 | 0.74 | EPHX1 (1.00) | EPHX1RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL34468086 | 0.74 | RAB9A (1.00) | EPHX1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL43922 | 0.74 | TSHR (0.67) | POLBRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL30504205 | 0.74 | TSHR (0.67) | POLBRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL12852553 | 0.73 | EPHX1 (0.67) | EPHX1POLBRAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-A1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115836-A1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | WO | disclosed |