Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584550 | 0.77 | EPHX1 (0.73) | POLBALDH1A1KDM4EPTPN1EPHX1 | |
| Hydrochloric Acid SCHEMBL4862375 | 0.74 | PTPN1 (0.51) | ALDH1A1KDM4EPTPN1OPRM1OPRK1 | |
| SCHEMBL2065774 | 0.74 | PTPN1 (0.61) | POLBALDH1A1PTPN1OPRM1OPRK1 | |
| SCHEMBL583543 | 0.72 | EPHX1 (0.66) | POLBALDH1A1KDM4EPTPN1EPHX1 | |
| SCHEMBL4582840 | 0.72 | PTPN1 (0.63) | POLBALDH1A1KDM4EPTPN1OPRM1 | |
| SCHEMBL27587662 | 0.72 | POLB (0.55) | POLBALDH1A1KDM4EPTPN1OPRM1 | |
| SCHEMBL30791550 | 0.71 | PTPN1 (0.61) | POLBALDH1A1PTPN1OPRM1OPRK1 | |
| SCHEMBL951041 | 0.71 | PTPN1 (0.61) | POLBALDH1A1PTPN1OPRM1OPRK1 | |
| SCHEMBL4808309 | 0.71 | PTPN1 (0.61) | POLBALDH1A1PTPN1OPRM1OPRK1 | |
| SCHEMBL5524103 | 0.71 | POLB (0.54) | POLBALDH1A1KDM4EPTPN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-A1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115836-A1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | WO | disclosed |