Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114677 | 0.92 | AVPR2 (0.49) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 | |
| SCHEMBL5836585 | 0.85 | AVPR2 (0.48) | AVPR1AAVPR2ROCK2 | |
| SCHEMBL5835303 | 0.85 | AVPR1A (0.51) | AVPR1AAVPR2 | |
| SCHEMBL5785098 | 0.84 | AVPR2 (0.50) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 | |
| SCHEMBL7115671 | 0.82 | AVPR2 (0.48) | AVPR1AAVPR2ROCK2 | |
| SCHEMBL5787329 | 0.81 | AVPR1A (0.46) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 | |
| SCHEMBL5786882 | 0.81 | AVPR2 (0.43) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 | |
| SCHEMBL5783950 | 0.81 | AVPR2 (0.40) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 | |
| SCHEMBL5786189 | 0.81 | AVPR2 (0.48) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 | |
| SCHEMBL7112850 | 0.81 | AVPR2 (0.42) | TSHRSMN1; SMN2AVPR1AAVPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109193-B2 | Tricyclic diazepines tocolytic oxytocin receptor antagonists | WYETH (US) | 2006-09-19 | — | — | US | claimed |
| US-20030008863-A1 | Novel tricyclic diazepines tocolytic oxytocin receptor antagonists | WYETH | 2003-01-09 | — | — | US | claimed |
| US-20030008863-A1 | Novel tricyclic diazepines tocolytic oxytocin receptor antagonists | WYETH | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008863-A1 | Novel tricyclic diazepines tocolytic oxytocin receptor antagonists | OXTR, OPRL1, HCRTR2 | TSHR 169/4885SMN1; SMN2 2129/4885AVPR1A 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.