Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.71 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.47 |
| ▸ | PDE2A | O00408 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835835 | 0.93 | TBXA2R (0.60) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5836698 | 0.89 | TBXA2R (0.57) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5835634 | 0.89 | TBXA2R (0.56) | TBXA2RPTGDR2PTGDR | |
| SCHEMBL5834981 | 0.89 | TBXA2R (0.56) | TBXA2RPTGDR2PTGDR | |
| SCHEMBL5836349 | 0.84 | TBXA2R (0.78) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5773893 | 0.83 | TBXA2R (1.00) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5836050 | 0.83 | TBXA2R (0.49) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5777801 | 0.81 | TBXA2R (0.71) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5777761 | 0.80 | TBXA2R (0.89) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5835366 | 0.78 | TBXA2R (0.44) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |