Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5836339 | 1.00 | TBXA2R (0.31) | TBXA2RIDO1NLRP3 | |
| SCHEMBL5836378 | 0.88 | — | — | |
| SCHEMBL5835473 | 0.85 | TBXA2R (0.31) | TBXA2RIDO1 | |
| SCHEMBL5772760 | 0.82 | PTGDR (0.39) | TBXA2R | |
| SCHEMBL5776344 | 0.80 | TBXA2R (0.38) | TBXA2RNLRP3 | |
| SCHEMBL5835600 | 0.78 | GLRA1 (0.40) | — | |
| SCHEMBL5797215 | 0.72 | TBXA2R (0.36) | TBXA2R | |
| SCHEMBL1253055 | 0.71 | — | — | |
| SCHEMBL5835091 | 0.71 | PTGS2 (0.31) | — | |
| SCHEMBL6730215 | 0.71 | PTGS2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |