SCHEMBL5836366

SCHEMBL5836366

COC(=O)CCCCC1(C(=O)OC)CC2C=CC1C2

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 8/20 0.39
TSHR P16473 3/20 0.36
EPHX1 P07099 2/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
PPARG P37231 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
NR2E3 Q9Y5X4 2/20 0.32
NCOR2 Q9Y618 2/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5838040 0.96 TSHR (0.37) EPHX2TSHREPHX1PPARGTDP1
SCHEMBL5838282 0.91 TSHR (0.33) EPHX2TSHRCYP2D6CYP2C19CA12
SCHEMBL5837346 0.90 EPHX2 (0.33) EPHX2TSHRALDH1A1CYP2D6CYP2C19
SCHEMBL18621596 0.86 POLA1 (0.36) EPHX2TSHRALDH1A1CYP2D6CYP2C19
SCHEMBL5837438 0.86 EPHX2 (0.34) EPHX2TSHRALDH1A1TDP1CYP2D6
SCHEMBL5837042 0.85 TSHR (0.33) EPHX2TSHRCYP2D6CYP2C19
SCHEMBL22064251 0.85 CYP2D6 (0.36) EPHX2ALDH1A1CYP2D6CYP2C19
SCHEMBL5837547 0.82 CYP2D6 (0.33) MAPTCYP2D6CYP2C19
SCHEMBL5836559 0.82 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL11465814 0.82 CYP2D6 (0.35) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100386357-C Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORP (JP) 2008-05-07 CN disclosed
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
CN-1659205-A Norbornene-based ring-opening polymer, hydrogenation product of norbornene-based ring-opening polymer, and method for producing same ZEON CORP (JP) 2005-08-24 CN disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed