Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 20/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776610 | 0.86 | TBXA2R (0.63) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL5835901 | 0.74 | TBXA2R (0.69) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL5778581 | 0.74 | TBXA2R (0.61) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL5837002 | 0.68 | TBXA2R (0.71) | TBXA2RPTGDR2 | |
| SCHEMBL5836349 | 0.67 | TBXA2R (0.78) | TBXA2RPTGDR2 | |
| SCHEMBL5835920 | 0.66 | TBXA2R (0.39) | TBXA2RPTGDR2 | |
| SCHEMBL5836332 | 0.66 | TBXA2R (0.39) | TBXA2RPTGDR2 | |
| SCHEMBL5834967 | 0.65 | TBXA2R (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL5777316 | 0.65 | TBXA2R (1.00) | TBXA2RPTGDR2 | |
| SCHEMBL5777816 | 0.64 | TBXA2R (0.74) | TBXA2RPTGER1PTGFRPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |