SCHEMBL5838301

SCHEMBL5838301

COC(=O)CC1(C(=O)OC(C)C)CC2C=CC1C2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5836559 0.88 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL5837258 0.86 CYP2D6 (0.33) SMN1; SMN2CYP2D6CYP2C19
SCHEMBL5836976 0.83 CYP2D6 (0.35) SMN1; SMN2CYP2D6CYP2C19
SCHEMBL5837137 0.82 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL5837900 0.82 CYP2D6 (0.31) CYP2D6CYP2C19EPHX2
SCHEMBL5836953 0.81 CYP2D6 (0.35) SMN1; SMN2CYP2D6CYP2C19EPHX2
SCHEMBL5836367 0.81 CYP2D6 (0.33) CYP2D6CYP2C19EPHX2
SCHEMBL5836998 0.79 EPHX2 (0.34) CYP2D6CYP2C19EPHX2
SCHEMBL5837108 0.77 CYP2D6 (0.35) SMN1; SMN2CYP2D6CYP2C19EPHX2
SCHEMBL5836347 0.76 CYP2D6 (0.35) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100386357-C Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORP (JP) 2008-05-07 CN disclosed
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
CN-1659205-A Norbornene-based ring-opening polymer, hydrogenation product of norbornene-based ring-opening polymer, and method for producing same ZEON CORP (JP) 2005-08-24 CN disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed