SCHEMBL5838503

SCHEMBL5838503

CCCCC(OC(=O)C=CC(=O)O)[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.47
ACHE P22303 1/20 0.40
BACE1 P56817 1/20 0.40
ATM Q13315 1/20 0.36
CTSK P43235 1/20 0.35
TSHR P16473 1/20 0.35
CA2 P00918 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28386996 1.00 HCAR2 (0.47) HCAR2ACHEBACE1ATMCTSK
SCHEMBL28383335 1.00 HCAR2 (0.47) HCAR2ACHEBACE1ATMCTSK
SCHEMBL20377934 0.94 ATM (0.40) HCAR2ACHEBACE1ATMCTSK
SCHEMBL20377937 0.94 ATM (0.40) HCAR2ACHEBACE1ATMCTSK
SCHEMBL21767950 0.84 HCAR2 (0.38) HCAR2ATMCTSKTSHR
SCHEMBL21767938 0.80 HCAR2 (0.52) HCAR2TSHRCA2
SCHEMBL3482324 0.79 HCAR2 (0.55) HCAR2ACHEBACE1ATMTSHR
SCHEMBL11407409 0.79 HCAR2 (0.55) HCAR2ACHEBACE1ATMTSHR
SCHEMBL3482317 0.79 HCAR2 (0.55) HCAR2ACHEBACE1ATMTSHR
SCHEMBL2102444 0.76 HCAR2 (0.56) HCAR2ACHEBACE1ATMCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060276113-A1 Polishing cloth, polishing apparatus and method of manufacturing semiconductor devices HIRABAYASHI HIDEAKI 2006-12-07 US disclosed