SCHEMBL21767950

SCHEMBL21767950

CCCC(OC(=O)/C=C\C(=O)OC(CCC)[Si](C(C)C)(C(C)C)C(C)C)[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.38
ATM Q13315 1/20 0.34
CTSK P43235 1/20 0.31
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20377934 0.89 ATM (0.40) HCAR2ATMCTSKTDP1TSHR
SCHEMBL20377937 0.89 ATM (0.40) HCAR2ATMCTSKTDP1TSHR
SCHEMBL28383335 0.84 HCAR2 (0.47) HCAR2ATMCTSKTSHR
SCHEMBL5838503 0.84 HCAR2 (0.47) HCAR2ATMCTSKTSHR
SCHEMBL28386996 0.84 HCAR2 (0.47) HCAR2ATMCTSKTSHR
SCHEMBL21767937 0.79 HCAR2 (0.39) HCAR2TSHR
SCHEMBL2144575 0.75 ATM (0.40) HCAR2ATMCTSKTDP1TSHR
SCHEMBL5838908 0.75 ATM (0.40) HCAR2ATMCTSKTDP1TSHR
SCHEMBL4583113 0.74 HCAR2 (0.45) HCAR2ATMCHRM1AKR1A1CHRM3
SCHEMBL9328093 0.74 HCAR2 (0.45) HCAR2ATMCHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617240-B1 VEHICLE RESIN FOR AN ANTIFOULING COATING NIPPON PAINT MARINE COATINGS CO LTD (JP) 2021-12-01 EP disclosed
US-11111406-B2 Copolymer and antifouling coating composition containing the same NIPPON PAINT MARINE COATINGS CO., LTD. (JP) 2021-09-07 US disclosed
US-20210024770-A1 COPOLYMER AND ANTIFOULING COATING COMPOSITION CONTAINING THE SAME NIPPON PAINT MARINE COATINGS CO., LTD. (JP) 2021-01-28 US disclosed
EP-3617240-A1 COPOLYMER AND ANTI-FOULING PAINT COMPOSITION CONTAINING SAME Nippon Paint Marine Coatings Co., Ltd. (JP) 2020-03-04 EP disclosed