Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208704 | 0.79 | NPC1 (0.41) | HTR2CMEN1KMT2ANPSR1ELANE | |
| SCHEMBL1669072 | 0.78 | MEN1 (0.57) | HTR2CMEN1KMT2ANPSR1TMEM97 | |
| SCHEMBL72092 | 0.78 | MEN1 (0.57) | HTR2CMEN1KMT2ANPSR1TMEM97 | |
| SCHEMBL9173427 | 0.77 | AGTR2 (0.47) | HTR2CMEN1KMT2ANPSR1ELANE | |
| SCHEMBL9173431 | 0.77 | AGTR2 (0.47) | HTR2CMEN1KMT2ANPSR1ELANE | |
| SCHEMBL5149957 | 0.77 | AGTR2 (0.47) | HTR2CMEN1KMT2ANPSR1ELANE | |
| SCHEMBL5155368 | 0.76 | MEN1 (0.43) | HTR2CMEN1KMT2ANPSR1ELANE | |
| SCHEMBL914595 | 0.75 | SMN1; SMN2 (0.56) | HTR2CMEN1KMT2ANPSR1 | |
| SCHEMBL6961448 | 0.75 | SMN1; SMN2 (0.56) | HTR2CMEN1KMT2ANPSR1 | |
| SCHEMBL2621368 | 0.75 | MEN1 (0.53) | HTR2CMEN1KMT2ANPSR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167277-A1 | New aziridine derivatives and their preparation methods | SAMCHULLY PHARM. CO., LTD. (KR) | 2006-07-27 | — | — | US | disclosed |
| US-7049447-B2 | Aziridine derivatives and their preparation methods | SAMCHULLY PHARM. CO.,LTD. (KR) | 2006-05-23 | — | — | US | disclosed |
| US-20040097480-A1 | Aziridine derivatives and their preparation methods | SAMCHULLY PHARM. CO., LTD. (KR) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167277-A1 | New aziridine derivatives and their preparation methods | AAAS, AZI2, ATXN2L | HTR2C 120/4885MEN1 4087/4885KMT2A 792/4885 |
| US-20040097480-A1 | Aziridine derivatives and their preparation methods | AZI2, AAAS, HRH2 | HTR2C 322/4885MEN1 3313/4885KMT2A 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.