SCHEMBL5839282

SCHEMBL5839282

FC(F)(F)c1ccccc1NCCNc1ccccc1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.57
ALDH1A1 P00352 3/20 0.57
TDP1 Q9NUW8 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
GAA P10253 1/20 0.45
IDO1 P14902 2/20 0.44
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 2/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5840060 0.91 ALDH1A1 (0.53) POLBALDH1A1TDP1L3MBTL1MAPT
SCHEMBL20873191 0.88 POLB (0.50) POLBALDH1A1TDP1L3MBTL1GAA
SCHEMBL6236003 0.88 POLB (0.50) POLBALDH1A1TDP1L3MBTL1MAPT
SCHEMBL11935548 0.86 POLB (0.49) POLBALDH1A1TDP1L3MBTL1GAA
SCHEMBL9225197 0.85 ALDH1A1 (0.55) POLBALDH1A1TDP1L3MBTL1MAPT
SCHEMBL9221569 0.85 POLB (0.47) POLBALDH1A1TDP1L3MBTL1GAA
SCHEMBL8165099 0.85 ALDH1A1 (0.48) POLBALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL6236117 0.83 EPHX2 (0.50) POLBALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL4975136 0.83 ALDH1A1 (0.53) POLBALDH1A1TDP1L3MBTL1MAPT
SCHEMBL31361988 0.83 ALDH1A1 (0.53) POLBALDH1A1TDP1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6992034-B2 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2006-01-31 US disclosed
US-20050009690-A1 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATIONS, U.S.A. 2005-01-13 US disclosed