Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSPB1 | P04792 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829398 | 0.81 | HTT (0.66) | ALDH1A1HIF1AHSPB1HTTTDP1 | |
| SCHEMBL122944 | 0.81 | HTT (0.66) | ALDH1A1HIF1AHSPB1HTTTDP1 | |
| SCHEMBL16177443 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HIF1AHSPB1HTTHSD17B10 | |
| SCHEMBL25796968 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HIF1AHSPB1HTTHSD17B10 | |
| SCHEMBL29739501 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HIF1AHSPB1HTTTDP1 | |
| SCHEMBL3639867 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HIF1AHSPB1HTTTDP1 | |
| SCHEMBL31506375 | 0.77 | CYP19A1 (0.57) | ALDH1A1HIF1AHSPB1HTTTDP1 | |
| SCHEMBL25797159 | 0.77 | CYP19A1 (0.57) | ALDH1A1HIF1AHSPB1HTTTDP1 | |
| SCHEMBL4402520 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HIF1AHSPB1HTTHSD17B10 | |
| SCHEMBL3643810 | 0.77 | HTT (0.54) | ALDH1A1HIF1AHSPB1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138425-B2 | Phthalimide carboxylic acid derivatives | OXFORD GLYCOSCIENCE (UK) LTD. (GB) | 2006-11-21 | — | — | US | disclosed |
| US-20050203153-A1 | Phthalimide carboxylic acid derivatives | OXFORD GLYCOSCIENCE (UK) LTD. (GB) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203153-A1 | Phthalimide carboxylic acid derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, IDH1 | ALDH1A1 160/4885HIF1A 113/4885HSPB1 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.