Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.78 |
| ▸ | FABP4 | P15090 | 2/20 | 0.78 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.78 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839970 | 0.89 | MRGPRX4 (0.67) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL5839536 | 0.88 | FABP4 (1.00) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL9824901 | 0.87 | FABP3 (0.64) | FABP3FABP4FABP5MRGPRX4NR4A2 | |
| SCHEMBL5839914 | 0.85 | FABP4 (0.88) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL5663405 | 0.85 | FABP4 (0.88) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL1388155 | 0.85 | HTT (0.77) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL8883421 | 0.85 | FABP3 (0.62) | FABP3FABP4FABP5MRGPRX4ALDH1A1 | |
| SCHEMBL3806442 | 0.83 | MRGPRX4 (0.71) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL22480892 | 0.83 | MRGPRX4 (1.00) | FABP3FABP4FABP5MRGPRX4TP53 | |
| SCHEMBL3983385 | 0.83 | TP53 (0.74) | FABP3FABP4FABP5MRGPRX4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |
| US-5677465-A | FUNGICIDE, HERBICIDE, PLANT GROWTH REGULATOR | SHIONOGI & CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5466661-A | Benzaldehyde oxime derivatives, production and use thereof | SHIONOGI & CO., LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0633252-A1 | Benzaldehyde oxime derivatives, production and use thereof | SHIONOGI & CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |