Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799578 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL8553937 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL9322416 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL491616 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL7230416 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL491983 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL21799504 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL21799790 | 1.00 | HRH3 (0.75) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| SCHEMBL10480715 | 0.98 | HRH3 (0.71) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT | |
| Hydrazine SCHEMBL8558416 | 0.98 | HRH3 (0.71) | HRH3SMN1; SMN2KEAP1SIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252115-B1 | ADDING TO THE DISTILLATION MIXTURE AN INERT COMPOUND HAVING A BOILING POINT HIGHER THAN THE AMINE | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | claimed |
| EP-0964847-A1 | METHOD FOR SEPARATING AN IMINE FROM A MIXTURE CONTAINING AN AMINE AND AN IMINE | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-22 | — | — | EP | claimed |
| WO-1998034900-A1 | METHOD FOR SEPARATING AN IMINE FROM A MIXTURE CONTAINING AN AMINE AND AN IMINE | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-13 | — | — | WO | claimed |
| US-5216152-A | To yield hexamethyleneimine, hexamethylenediamine, and n-/6-aminohexyl/hexamethyleneimine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-01 | — | — | US | claimed |
| EP-4613735-A1 | METHOD FOR PREPARING HEXAMETHYLENEDIAMINE | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-118477638-A | Supported Ru-based catalyst, preparation method thereof and application thereof in preparation of hexamethylenediamine by amination of cyclohexylimine | 开滦（集团）有限责任公司 | 2024-08-13 | — | — | CN | disclosed |
| US-20230390747-A1 | AMINATION CATALYST AND PREPARATION AND USE THEREOF | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2023-12-07 | — | — | US | disclosed |
| US-20230381757-A1 | AMINATION CATALYST AND PREPARATION AND USE THEREOF | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2023-11-30 | — | — | US | disclosed |
| EP-4238648-A1 | AMINATION CATALYST AND PREPARATION AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2023-09-06 | — | — | EP | disclosed |
| EP-4238647-A1 | AMINATION CATALYST AND PREPARATION AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2023-09-06 | — | — | EP | disclosed |
| CN-112898163-B | Method for preparing 1, 6-hexamethylene diamine by ammoniation of hexamethylene imine | 中国科学院大连化学物理研究所 | 2022-06-24 | — | — | CN | disclosed |
| CN-112898164-B | Method for preparing 1, 6-hexamethylene diamine from 5-hydroxymethylfurfural | 中国科学院大连化学物理研究所 | 2022-03-04 | — | — | CN | disclosed |
| US-5288911-A | Catalytic reaction of alkandiols with ammonia | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| US-5216149-A | Sequential pyrolysis using different temperatures, catalysts and supports to provide selective recovery of desired product | MIDWEST RESEARCH INSTITUTE (US) | 1993-06-01 | — | — | US | disclosed |
| US-5216152-A | To yield hexamethyleneimine, hexamethylenediamine, and n-/6-aminohexyl/hexamethyleneimine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5216152-A | To yield hexamethyleneimine, hexamethylenediamine, and n-/6-aminohexyl/hexamethyleneimine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1992022528-A2 | CONTROLLED CATALYTIC AND THERMAL SEQUENTIAL PYROLYSIS AND HYDROLYSIS OF MIXED POLYMER WASTE STREAMS TO SEQUENTIALLY RECOVER MONOMERS OR OTHER HIGH VALUE PRODUCTS | MIDWEST RESEARCH INSTITUTE (US) | 1992-12-23 | — | — | WO | disclosed |
| EP-0510382-A2 | Method of preparation of alpha-omega-aminoalcohols | BASF Aktiengesellschaft (DE) | 1992-10-28 | — | — | EP | disclosed |
| US-4290946-A | CONTINUOUS PROCESSING, HEXAMETHYLENEDIAMINE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-09-22 | — | — | US | disclosed |
| US-4014933-A | Production of amines from alcohols | BASF AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |