SCHEMBL5839725

SCHEMBL5839725

Cc1cccc(N(c2ccccc2)c2ccccc2Nc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.50
THRB P10828 1/20 0.42
PKM P14618 1/20 0.42
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 4/20 0.41
GAA P10253 3/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
GLA P06280 1/20 0.41
RECQL P46063 1/20 0.41
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HSP90AA1 P07900 1/20 0.38
EGFR P00533 1/20 0.38
SRC P12931 1/20 0.38
HPGD P15428 2/20 0.38
ALDH1A1 P00352 3/20 0.38
CXCR2 P25025 2/20 0.38
ATM Q13315 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1742394 0.92 NPSR1 (0.56) NPSR1THRBPKMMEN1KMT2A
SCHEMBL30296910 0.85 MAPT (0.48) NPSR1MEN1KMT2AMAPTGAA
SCHEMBL3175953 0.85 MAPT (0.48) NPSR1MEN1KMT2AMAPTGAA
SCHEMBL30242039 0.82 ACHE (0.44) NPSR1THRBPKMMEN1KMT2A
SCHEMBL29733508 0.82 ACHE (0.44) NPSR1THRBPKMMEN1KMT2A
SCHEMBL331098 0.82 ACHE (0.44) NPSR1THRBPKMMEN1KMT2A
SCHEMBL11973528 0.81 NPSR1 (0.46) NPSR1THRBPKMMEN1KMT2A
SCHEMBL12012945 0.81 NPSR1 (0.61) NPSR1THRBPKMMEN1KMT2A
SCHEMBL3463650 0.81 NPSR1 (0.61) NPSR1THRBPKMMEN1KMT2A
SCHEMBL17426604 0.81 NPSR1 (0.61) NPSR1THRBPKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891121-B1 ORGANIC ELECTROLUMINESCENT ELEMENTS TDK CORP (JP) 2012-09-26 EP disclosed
US-7097918-B2 Organic EL device TDK CORPORATION (JP) 2006-08-29 US disclosed
US-20040110030-A1 uses an optical and electronic functional material less susceptible to physical, photochemical and electrochemical changes, and gives out light emissions of various colors with high reliability and high light emission; electroluminescent (EL) TDK CORPORATION (JP) 2004-06-10 US disclosed
US-6623872-B2 Including a hole injecting layer comprising a specific triarylamine oligomer so that low driving voltage, stable light emission, high quality display images and high heat resistance are achievable. TDK CORPORATION (JP) 2003-09-23 US disclosed
US-20020102434-A1 Organic EL device TDK CORPORATION (JP) 2002-08-01 US disclosed
US-6344283-B1 OPTICAL AND ELECTRONIC NON-STRUCTURAL TERT-AMINOPHENYLAMINO-SUBSTITUTED MULTIPHENYLENEDIAMINE MATERIAL PARTICULARLY LESS SUSCEPTIBLE TO PHYSICAL CHANGES, PHOTOCHEMICAL CHANGES AND ELECTROCHEMICAL CHANGES TDK CORPORATION (JP) 2002-02-05 US disclosed
EP-0891121-A1 ORGANIC ELECTROLUMINESCENT ELEMENTS TDK Corporation (JP) 1999-01-13 EP disclosed