Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | CPA3 | P15088 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259232 | 0.92 | TDP1 (0.56) | TDP1FOLH1SMN1; SMN2ADRA1ASLC1A3 | |
| SCHEMBL23060312 | 0.92 | TDP1 (0.56) | TDP1FOLH1SMN1; SMN2ADRA1ASLC1A3 | |
| SCHEMBL6631810 | 0.86 | TDP1 (0.54) | TDP1FOLH1SMN1; SMN2ADRA1ASLC1A3 | |
| SCHEMBL450856 | 0.77 | TDP1 (0.65) | TDP1FOLH1SMN1; SMN2ADRA1ASLC1A3 | |
| SCHEMBL3285462 | 0.76 | TDP1 (0.72) | TDP1FOLH1CPA1CPB1CPA3 | |
| SCHEMBL786389 | 0.76 | TDP1 (0.72) | TDP1FOLH1CPA1CPB1CPA3 | |
| SCHEMBL9643869 | 0.76 | TDP1 (0.46) | TDP1FOLH1CPA1CPB1CPA3 | |
| SCHEMBL25414620 | 0.74 | TDP1 (0.68) | TDP1FOLH1CPA1CPB1CPA3 | |
| Tricarballylic Acid SCHEMBL34866 | 0.73 | FOLH1 (0.65) | TDP1FOLH1CPA1CPB1CPA3 | |
| Tricarballylic Acid SCHEMBL1821947 | 0.73 | FOLH1 (0.65) | TDP1FOLH1CPA1CPB1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225272-B1 | PEPTIDES DERIVED FROM NCAM (FGLS) | ENKAM PHARMACEUTICALS AS (DK) | 2015-10-21 | — | — | EP | disclosed |
| EP-1765861-B1 | FGFR BINDING PEPTIDES | ENKAM PHARMACEUTICALS AS (DK) | 2012-02-15 | — | — | EP | disclosed |
| EP-2225272-A2 | NOVEL PEPTIDES DERIVED FROM NCAM (FGLS) | Enkam Pharmaceuticals A/S (DK) | 2010-09-08 | — | — | EP | disclosed |
| EP-1660539-B1 | COMPOUNDS COMPRISING LPA | ENKAM PHARMACEUTICALS AS (DK) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009068042-A2 | NOVEL PEPTIDES DERIVED FROM NCAM (FGLS) | ENKAM PHARMACEUTICALS A/S (DK) | 2009-06-04 | — | — | WO | disclosed |
| EP-1765861-A2 | FGFR BINDING PEPTIDES | Enkam Pharmaceuticals A/S (DK) | 2007-03-28 | — | — | EP | disclosed |
| EP-1660539-A2 | COMPOUNDS COMPRISING LPA | Enkam Pharmaceuticals A/S (DK) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014623-A9 | COMPOUNDS COMPRISING LPA | — | 2006-03-23 | — | — | WO | disclosed |
| WO-2005123759-A2 | FGFR BINDING PEPTIDES | ENKAM PHARMACEUTICALS A/S (DK) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005014623-A2 | COMPOUNDS COMPRISING LPA | ENKAM PHARMACEUTICALS A/S (DK) | 2005-02-17 | — | — | WO | disclosed |